This book gathers original research papers presented at the 4th International Conference on Computational Mathematics and Engineering Sciences, held at Akdeniz University, Antalya, Turkey, on 20–22 April 2019. Focusing on computational methods in science, mathematical tools applied to engineering, mathematical modeling and new aspects of analysis, the book discusses the applications of mathematical modelling in areas such as health science, engineering, computer science, social science, and economics. It also describes a wide variety of analytical, computational, and numerical methods.