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Description - The Causes and Consequences of Chromosomal Aberrations by Ilan R. Kirsch

Aimed at geneticists, molecular biologists and cytogeneticists, this book explores one of the most dramatic examples of genomic instability - chromosomal aberrations. It describes new techniques used to map genes within the human genome, studies chromosomal aberrations at the cellular level and defines the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The book also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations which offer separate instructive treatises on specific malignancies.

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