This volume illuminates the interplay among biological, psychological, and social-contextual processes in the development of prevalent clinical problems. Bruce F. Pennington explains the variety of methods used to investigate the mind-brain connection, including behavioral and molecular genetics, studies of brain structure and function, neuropsychology, and treatment studies. Shedding light on where mental disorders come from, how they develop, and why they are so common, the book also examines the implications for diagnosis, treatment, and prevention.