Fifteen years after The Dunwall Plague, the Empire begins to plunge into chaos after Empress Emily Kaldwin is suddenly dethroned by an 'otherworldly usurper', and becomes an outlaw to society. Determined to claim it back, Emily follows the steps of her father, Corvo Attano, in becoming an Assassin. Armed with the Outsider's mark, she intends to reclaim her title and restore power to what had been lost.

Dishonored is a stealth action-adventure video game released worldwide in October 2012 for Microsoft Windows, PlayStation 3, and Xbox 360. Set in the fictional, plague-ridden industrial city of Dunwall, Dishonored follows the story of Corvo Attano, bodyguard to the Empress of the Isles. He is framed for her murder and forced to become an assassin, seeking revenge on those who conspired against him. Corvo is aided in his quest by the Loyalists - a resistance group fighting to reclaim Dunwall, and the Outsider - a powerful being who imbues Corvo with magical abilities.