Retired burlesque queen Beatrice Shelton desperately needs a vacation and NOT another trip up to Helen Georgia to see that "precious little German village for the umpteenth time." A Sassy Seniors Cruise through the Caribbean may be just the ticket if she can just convince her best friend Eaddy Mae Clayton to stop praying and go with her. Unfortunately things have not been very pleasant at Magnolia Place Assisted Living since Nurse Pat Jones began working there. The newest resident Imogene Fletcher is suddenly losing her memory. Maude Jenkins is obsessed with her favorite soap opera and planning her own funeral. Sam Smith retired Elvis impersonator keeps trying to bed every woman in the building. A mystery unfolds with laughter as the gals try to outsmart the evil Nurse Pat Jones and figure out why so many residents have been moved to "the dark side " what exactly IS that mysterious pill and what happened to Doctor Head? Hilarity ensues as Imogene goes undercover and Maude enters the Miss Magnolia Senior Citizen Pageant to throw Pat off their trail. If they can solve the mystery they may make it to the cruise ship after all.