This book presents a comparative diagnosis of conditions similar to irritable bowel syndrome, assessment and elimination of abdominal pain, visceral hypersensitivity, and quality of life indicators for irritable bowel syndrome. At the same time, the importance of pro-inflammatory and anti-inflammatory cytokines in the diagnosis of irritable bowel syndrome is described. This monograph also provides detailed reviews and analysis of scientific papers by other authors on the problems of irritable bowel syndrome. The monograph can be used in practice as an important guide for students of medical institutions, clinical residents, masters, therapists and gastroenterologists.