Description - The Molecular Pathology of Autoimmune Disease by Constantin Bona
Of the diverse disorders afflicting humans, a wide spectrum of systematic diseases, such as lupus, rheumatiod arthritis and organ-specific diseases, such as myasthenia gravis, thyroiditis and juvenile diabetes, are wholly or partially attributable to autoimmunity. As yet, there is no unifying concept to explain the etiology of the many clinically diverse autoimmune disorders. Today, efforts to unravel the mysteries of these diseases are prominent in immunological research, and the progress in this area continues to advance. This book explores the molecular pathology of autoimmune diseases in four sections: cellular and molecular basis of autoimmunity; systemic autoimmune diseases; organ-specific autoimmune diseases; and autoimmunity associated with diseases. Studies in humans and corresponding animal models, as well as basic aspects of immunology related to autoimmune diseases, are described.
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