This Special Issue focuses on the prevalence of obesity and hypertension, shedding light on several critical aspects of these conditions. It underscores the profound effects of obesity and sedentary lifestyles on metabolic and cardiovascular health, highlighting the alarming disparities in obesity rates among adolescents. Furthermore, it examines the cardiovascular risk factors that have emerged in the wake of the COVID-19 pandemic, emphasizing the need for a comprehensive approach to public health strategies.