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Description - Radioprotectors by Edward A. Bump

It is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research.
Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics:oEarly research on radioprotectorsoWR-2721, an aminothiol prodrug, as a radioprotectoroNew results with naturally occurring thiolsoNitroxides as effective radioprotectors in vitro and in vivooRadioprotection observed with radical scavengers or antioxidantsoBone marrow radioprotection with cytokines and biological modifiersoMultiple mechanisms of altering radiation response by eicosanoidsoVascular response to radiation and the importance of vascular damage to normal tissue oModifiers of radiation-induced apoptosisoSurvey of clinical trials with radioprotectorsRadiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.

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