This time, forced against his will into the role of savior, he must contend with The Nexus, a terrifying and seductive alien intelligence. The entity, a parasite similar to the Queen in a nest of wasps, gave birth to a mutant strain that showed signs of independent thought. Billy, a carrier of the virus, by virtue of his unique bloodline, has suppressed the forceful voice of the hive. The last member of his family, he alone has reaped the benefits of belonging to the Nexus without actually being a part of it.

Now, The Nexus has gathered her champions and is preparing to tip the world into darkness. Both sides are vying to win Billy's service, who must enlist the support of some unlikely allies in order to survive.

In the end, Billy must shoot, cut and plow over a host of enemies in order to reach a forgotten, blood soaked mountaintop. There, the fate of the world will be decided on the edge of a hunting knife.