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Description - The 2020-21 Guide to Medications for the Therapy of Diabetes Mellitus by John R. White

Newly updated to reflect the latest research and medical guidance, the 2020-21 Guide to Medications for the Treatment of Diabetes offers a bridge between drug handbooks and pharmacology texts.

Focusing entirely on diabetes drugs, this reference is divided into two sections:

  • Drugs used to manage hyperglycemia, and
  • Management of diabetic comorbidities.

The first section includes:

  • Pharmacologic Therapy for Type 1 Diabetes
  • Management of Hyperglycemia in Type 1 DM info from practical use of insulin, pathophysiology, treatment strategy
  • Insulins: RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2
  • Pharmacologic Therapy for Type 2 Diabetes
  • Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications
  • Biguanides
  • TZDs
  • SUs
  • Glinides
  • SGLT-2 Inhibitors
  • AGIs
  • DPP-IV inhibitors
  • GLP Ras
  • Amylin mimetics
  • BARs
  • DA-2 agonists

Each chapter in Section 1 includes:

  • Drug class overview and role in diabetes treatment
  • Pharmacology: a. Mechanism of action, b. Pharmacokinetics
  • Treatment Advantages/Disadvantages: General for the class, b. When applicable, a discussion of evidence that supports the benefits of using a particular drug in a class over another in the same class (eg, Avandia vs Actos)
  • Therapeutic Considerations: a. Significant Warnings/Precautions, b. Special Populations, c. Pharmacogenomics, d. Adverse effects and monitoring, e. Drug Interactions, f. Dosage and administration
  • Table with Doses and Dose Adjustments
  • List of important combination products
  • References
  • The second section includes:

    • Cardiovascular Disease and Risk Management
    • Microvascular Complications and Foot Care
    • Medications for the Management of Hypertension
    • Medications for the Management of Hyperlipidemia
    • Antiplatelet Therapy
    • Medications for Smoking Cessation
    • Medications for the Management of Neuropathy (peripheral and autonomic)
    • Medications for the Management of Nephropathy
    • Medications for the Management of Retinopathy
    • Medications for the Management of Depression
    • Medications for the Management of Hypoglycemia
    • Medications for the Management of Obesity
    • Immunizations in Patients with Diabetes

    Each chapter in Section 2 includes:

  • An overview of the condition or problem
  • Goals of treatment
  • Overview of the medications and rationale for the medications used for the problem
  • Overview of each class of medication
  • Overview of combination therapy: a. first combination, b. second combination
  • Doses and Dose Adjustments for the more salient medications
  • List of important combination products
  • References
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