In the race to create the Undefeatable Minion, Dr. Critchlore's longtime rival, Dr. Pravus, is winning. As Dr. Critchlore rallies his troops, Runt is kidnapped. As the last prince of Andirat, he must lead the rebellion in his home country.

Isolated from his minion friends, Runt grows suspicious of the rebels, who seem to be working with Dr. Pravus. Runt knows he must escape and tell Dr. Critchlore, but reaching him activates Runt's curse, giving him just days to live! His only chance for survival: Stop Dr. Pravus and win the allegiance of the witch who cursed him. Fortunately for Runt, he knows just the minions for the job.